78例伤寒、副伤寒临床分析  

Clinical analysis on 78 cases of typhoid fever and paratyphoid fever

作　　者：邓蕙[1] 余泽波[1] 段明纲[1] 

机构地区：[1]重庆医科大学临床学院感染科,重庆400016

出　　处：《重庆医科大学学报》2005年第1期143-145,共3页Journal of Chongqing Medical University

摘　　要：目的了解近年来重庆地区伤寒、副伤寒的临床特征。方法回顾性分析我院1999年1月～2003年12月5年间收治的伤寒、副伤寒病例。结果伤寒病例比重有下降趋势,副伤寒病例比重则从1999年的20%上升到2003年的55.6%。临床以发热、相对缓脉、脾大,血白细胞下降、腹泻为主要表现,玫瑰疹、表情淡漠较少见,大多数病人的热型以不规则或弛张热为主,典型的稽留热仅占25.6%。常见的并发症为中毒性肝炎和支气管肺炎。伤寒、副伤寒对氟喹诺酮类、第三代头孢菌素有很好的敏感性。结论部分病例临床表现已不典型;近年来副伤寒比重有上升的趋势;氟喹诺酮类药物仍为伤寒、副伤寒的首选药物。Objective:To investigate the clinical features of typhoid fever and paratyphoid fever in Chongqing.Methods:A retrospective study was designed to analyze 78 cases of typhoid fever and paratyphoid fever from 1999 to 2003.Results:The proportion of typhoid fever was decreased,but the proportion of paratyphoid fever rose from 20% in 1999 to 55.6% in 2003.The clinical manifestations included fever,relative bradycardia,hepatosplenomegaly,leukopenia and diarrhea,infrequently as roseola and indifferent expressions.The complications mostly manifested as toxic hepatitis and bronchopneumonia.Typhoid fever and paratyphoid fever were sensitive to fluoro -quinolones and the third generation cephalothins.Conclusion:In recent years proportion of paratyphoid fever tend to rise.Fluoro-quinolones still remain the drug of choice for the treatment of typhoid and paratyphoid fever.

关 键 词：伤寒 副伤寒 肥大氏反应 临床分析 

分 类 号：R516.3[医药卫生—内科学] R978.13[医药卫生—临床医学]