天然手性源在光学活性菊酸合成中的应用  

Application of Natural Chiral Resources in Synthesis of Optical Chrysanthemic Acids and Their Analogues

作　　者：邵瑞链[1] 杨敏华[1] 

机构地区：[1]南开大学元素有机化学研究所,天津300071

出　　处：《有机化学》1993年第4期347-353,共7页Chinese Journal of Organic Chemistry

摘　　要：本文概述了用天然手性源制取光学活性菊酸的近期进展。讨论了利用天然手性试剂、酶以及微生物等对外消旋菊酸进行拆分,以天然氨基酸等作为手性诱导试剂进行不对称合成以及利用萜类、碳水化合物、酒石酸等分子中天然存在的立体结构进行骨架改造和选择性合成。In this paper, the application of natural chiral resources in synthesis of chrysanthemic acidshas been reviewed. Special attention has been paid to resolve the racemic acids and stereoselectivesynthesis with some natural chiral compounds including in terpenoids, carbo-hydrates, amino acidsand tartaric acid.

关 键 词：菊酸 光学异构体 拆分 不对称诱导 立体选择性合成 

分 类 号：O623.61[理学—有机化学]