中西医结合治疗女性生殖道尖锐湿疣临床研究  

Clinical Study on Female Genital Condyloma Acuminata Treated by Integrated Chinese & Western Medicine

作　　者：吴育宁 全延 华苓[1] 付洁[1] 张巨明[1] 张晓辉[1] 

机构地区：[1]北京中医医院妇产科,100010

出　　处：《中国计划生育学杂志》2003年第12期738-741,共4页Chinese Journal of Family Planning

摘　　要：目的:探索用中西医结合方法治疗女性生殖道尖锐湿疣的疗效及机理。方法:对386例女性生殖道尖锐湿疣患者随机采用三氯醋酸局部治疗(对照组)与中西医结合治疗(中西医结合组)两种方法,用阴道镜协助判定疗效及复发率,并检测治疗前后免疫功能变化。结果:中西医结合组的总有效率优于对照组(P<0.05);复发率明显低于对照组(P<0.01)。中药治疗后CD3、CD4明显增高。结论:中西医结合治疗女性生殖道尖锐湿疣可以提高疗效,降低复发率。其机理可能与提高患者的细胞免疫功能有关。Objective: To investigate the efficacy and mechanism of integrated Chinese and western medicine treating female genital condyloma acuminata. Methods: 386 cases of condyloma acuminatum of female genital tract were randomly treated by two therapies: Chinese herbal medicine( CHM) taking by mouth and sitz bath combined with local use of trichloroacetic acid (TCA) (combination group) and TCA (control group). To compare the effective rate and recurrence rate with the help of colposcopy and to elucidate the therapeutics mechanism by detecting immune functions. Results: The total effective rate of the combination group was higher than that of the control group (P <0. 05) ; the recurrence rates of combination group was obvi-ously lower than control group (P <0. 01) . The levels of CD3 , CD4 were markedly increased after treatment of CHM. Con-clusion: Integrated CHM with TCA can increase the clinical efficacy and reduce recurrence. The mechanism may be connected with the rising of their cellular immune functions.

关 键 词：中西医结合疗法 女性 尖锐湿疣 临床研究 细胞免疫功能 发病机理 阴道镜 乳头瘤病毒 HPV 

分 类 号：R752.53[医药卫生—皮肤病学与性病学]