益寿汤对小鼠免疫和抗应激能力的影响  

The Effect of Yi Shou Tang on the Activityof Immunity and Antistress of Mice

作　　者：王丽莉[1] 刘福英[1] 张国红[1] 张永健[1] 杨小平[1] 李蕴山[1] 傅绍萱[1] 

机构地区：[1]河北医科大学药理教研室

出　　处：《中国实验动物学报》1996年第2期113-117,共5页Acta Laboratorium Animalis Scientia Sinica

摘　　要：给小鼠益寿汤１ｇ／ｋｇ，２ｇ／ｋｇ，４ｇ／ｋｇ灌胃连续７ｄ，分别检测其抗应激能力和免疫功能的变化。结果表明：益寿汤４ｇ／ｋｇ组小鼠较对照组负重游泳耗竭时间和常压耐缺氧生存时间明显延长，益寿汤２ｇ／ｋｇ和４ｇ／ｋｇ可提高小鼠耐寒能力，各剂量益寿汤均可显著提高小鼠血清溶血素及碳粒廓清吞噬数，但对迟发型变态反应无明显影响。i Shou Tang was given to mice orally in the doses of 1g. 2g and 4g/kg scperately for 7 days. The activities of immunity and antistress wereexamined. The results showed that the swimming time and the endurancehypoxia in the 4g/kg group taking Yi Shou Tang were much longer than thecontrol group. Yi Shou Tang in the doses of 2g and 4g/kg improved theanticold activity. Morcver, YiShou Tang with the doses of 1g 2g and 4g/kg increased the serum hemolysin andphagocytic index but it had nosignificant effects on the de layed-type hypersensitivity.

关 键 词：益寿 小鼠 免疫 碳粒廓清 血清溶血素 耐缺氧 迟发型变态反应 抗应激能力 耐寒能力 剂量 

分 类 号：Q959.64[生物学—动物学] R285.5[医药卫生—中药学]