神经端侧吻合术与侧侧吻合术再生能力比较的实验研究  

Comparison of the nerve regeneration of end-to-side neurorrhaphy and side-to-side neurorrhaphy: an experimental study

作　　者：陈振兵[1] 洪光祥[1] 王发斌[1] 康皓[1] 黄启顺[1] 翁雨雄[1] 

机构地区：[1]武汉华中科技大学同济医学院附属协和医院手外科,430022

出　　处：《中国实用手外科杂志》2001年第1期29-31,共3页

摘　　要：目的 比较周围神经端侧吻合与神经侧侧吻合术后神经再生的情况。方法Ｗｉｓｔａｒ大鼠２２只，分成 Ａ、Ｂ两组，每组 １１只。Ａ组：左侧腓总神经切断并在胚神经干上外膜开窗后，与胚神经于作端侧吻合；Ｂ组：左侧用腓总神经切断后与胫神经作侧侧吻合。术后３月，行形态学。电生理检查，辣根过氧化物酶（ＨＲＰ）逆行追踪法评价神经再生情况。结果 两组间神经纤维的数目、面积、神经传导速度以及背根神经节阳性神经元数目均无明显差异（Ｐ＞０．０５）。结论 神经端侧吻合术与神经侧侧吻合术的再生能力无明显差异。Objective To compare the nerve regeneration of end-to-side neurorrhaphy with that of end-to-side neurorrhaphy. Methods 22 Wistar rats were randomly divided into A B groups, with 11 rats each. In group A, the left common peroneal nerve was sectioned and its distal end was sutured laterly to the tibial nerve after removal of a window in the epineurium; In group B, the left common stump was sutured in paralell with the tibial nerve after removal of epineurium. 3 months after operation, morphlogy examination, electrophsiological examination and hoseradish peroxidas(Hill?) tracing were used to evaluate the nerve regeneration. Results The number and area of myelinated nerve, nerve conductive velocity and positive marked neurons of dorsal root ganglia made no significant difference between group A and group B(P > 0.05). Conclusion The capability of nerve regeneration in end-to-side neurorrhaphy and side-to-side neurorrhaphy is not different.

关 键 词：神经端侧吻合术 神经侧侧吻合术 神经再生能力 辣根过氧化物酶 逆行追踪法 

分 类 号：R651.3[医药卫生—外科学]