柞蚕雄蛾口服液毒理学与药理学研究  

A study on the safety and Phanmacology of "Oral Liquid for Silk Moth" (OLSM)

作　　者：吴景时[1] 王秀芬[1] 周金霞[1] 冯芹喜[1] 李荣[2] 李孟全[2] 吴宜艳[2] 杨履艳[2] 李鹰[3] 张晓莉[3] 罗萍[4] 陈慧芬 郭新民[6] 李亚娟[6] 孙玉花[6] 张德云 

机构地区：[1]牡丹江医学院抗衰老研究所 [2]牡丹江医学院药理教研室 [3]牡丹江医学院微免教研室 [4]牡丹江医学院血液病研究所 [5]市第一人民医院 [6]牡丹江医学院生化教研室 [7]不详

出　　处：《牡丹江医学院学报》1996年第2期1-2,共2页Journal of Mudanjiang Medical University

摘　　要：柞蚕雄蛾口服液系牡丹江医学院抗衰老研究所于1995年研制的新型中药制剂产品,采用牡丹江地产柞蚕雄蛾全虫经干燥后,按常规方法制成的复方口服液,亚急性毒性,慢性毒性,LD_(50)测定和耐受量试验;进行药理学实验研究包括免疫药理、生化药理,激素药理和抗衰老药理,证明该产品无毒性,不产生过敏反应,口服安全有效,具有明显促雄性样作用,增强免疫功能和抗衰老作用。A new-type complexherbs agent OLSM, The acute toxicity Subacute toxicity, accumulative toxicity, irritant effect, alleragic reaction and hemolytic effect of OLSM, a new oral vital funtion promoting and body resistance strengtheng chinese herb al medicine, were tested in rabbits, chikens and mice Is injected into the white little rats to perform th immune pharmacological experiment, The three experimental methods which we took are to test the functia of macrophage in its abdo-men, PF and T-lymphocyte esterase label The study shows that OLSM apparenty increase the immunityof the white little rats OLSM filled into stomach of mice.Result in oral liquid for male silk moth may low LPO in plasma and liver of mice.

关 键 词：口服液 药理学研究 毒理学 全虫 雄蛾 抗衰老研究 抗衰老药 产品 地产 法制 

分 类 号：R285.5[医药卫生—中药学] R282.74[医药卫生—中医学]