嗜多染红细胞微核技术研究LDM对抗烟碱所致遗传物质损伤作用  

Study on LDM resisting harm of genetic substance induced by nicotine with the technigue of micronculei of polychromaphilic erythrocyte

作　　者：王好生[1] 陈迪[1] 何孝忠 张真珍 尹光武[1] 游文凤[1] 刘运卿[1] 

机构地区：[1]河南医科大学遗传研究所,河南职工医学院,扶沟县公疗医院,杞县人民医院

出　　处：《中国优生与遗传杂志》1994年第F08期54-55,共2页Chinese Journal of Birth Health & Heredity

摘　　要：本文采用骨髓嗜多染红细胞微核技术，研究一种植物提取物（ＬＤＭ）对抗烟碱诱发细胞微核的致突变作用。实验结果显示，ＬＤＭ抗烟碱组的细胞微核率明显低于烟碱组的细胞微核率，两者有显著差异。实验证明。A substance named LDM that is con stracted from a plant has been studied to resist the mutation induced by nicotine,with the technigue of micronuclei of polychromaphilic erythrocytes in marrow.The results indicate that the freguencg of micronuclei in the group of LDM resisting nicotine is lower to that of the group of nicotine,and there are obvious differences between the groups. The study show the LDM has obvious effeetion of protecting cellular genetic substance from the harm induced by nicotine.

关 键 词：损伤作用 烟碱 遗传物质 骨髓嗜多染红细胞微核 细胞微核率 致突变作用 诱发 微核技术 保护 实验结果 

分 类 号：R285.5[医药卫生—中药学] R996.1[医药卫生—中医学]