不同穴位电针对脊髓背角神经元伤害性反应抑制作用的广泛性和特异性  

The Extensiveness and Specificity of Analgesia of Electroacupuncture(EA)at Different Points on the Nociceptive Responses of Neuron in Spinal Dorsal horn

作　　者：何晓玲[1] 朱兵[1] 刘乡[1] 徐卫东[1] 张守信[1] 

机构地区：[1]中国中医研究院针灸研究所,北京100700

出　　处：《针刺研究》1993年第4期271-275,共5页Acupuncture Research

摘　　要：实验用玻璃微电极细胞外记录大鼠脊髓背角会聚神经元对后爪伤害性刺激的反应,观察不同强度及不同穴位的电针对该神经元伤害性反应的影响。低强度(2V)电针与痛刺激近节段的下肢穴“足三里”对会聚神经元的伤害性反应有明显的抑制作用,而头面部的远节段穴“下关”则没有这种抑制作用。表现出穴位镇痛的特异性。高强度(18V)电针分别给予“足三里”或“下关”对该神元的伤害性反应均可引起明显而持久的抑制作用。表现出穴位镇痛的广泛性。The experipments were performed in anaesthetized rats.The responses of convergent neurons inspinal dorsal horn to noxious stimuli(10mA,2ms)given at the hindpaw receptive field were recordedextracellularly by glass microelectrodes.The effeets of EA on the nociceptive response were observed.EA was applied on ipsilateral“Zusanli”or“Xiaguan”point with high and low intensity.EA(18V,100Hz)applied on ipsilateral either“Zusanli”or“Xiaguan”could produce strong inhi-bition on nociceptive responses of convergent neurones(62.74±4.94% and 64.24±7.30%).EA(2V,100Hz)of“Zusanli”also obviously inhibited the noeiceptive responses(52.05±6.69%).Butthe same EA of“Xiaguan”lacked this inhibitory effect(9.50±7.67%).There was statistically sig-nificant difference between EA effects of“Zusanli”and“Xiaguan”(P<0.001)when intensity of EAis lower.These results guggested that analgesia of high intensity EA is extensive,but that of low intensityEA is produced only when the point is in the same or nearby spinal segment with nociceptive field,showing the extensiveness and specificity of EA analgesia of different points.

关 键 词：会聚神经元 伤害性反应 电针镇痛 

分 类 号：R245.97[医药卫生—针灸推拿学]