降脂通脉方治疗高脂血症的临床研究  

Clinical Study on Jiangzhitongmaifang in Treating Hperlipideproteinemia (HLP)

作　　者：王亚红[1] 吕唏滢[1] 秦腊梅[1] 赵明镜[1] 肖龙正 唐玲[1] 何兰英[1] 蒋学英[1] 郭维琴[1] 王硕仁[1] 鲁伟星[1] 

机构地区：[1]北京中医药大学,东直门医院,北京,100700 [2]台湾留学生

出　　处：《中国中医基础医学杂志》2002年第3期52-53,共2页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：国家自然科学基金资助项目 (No.395 70 877)

摘　　要：目的 :探讨中药治疗高脂血症的疗效及其作用机理。方法 :6 1例高脂血症患者随机分为中药降脂通脉口服液治疗组 (治疗组 )和西药洛伐他丁对照组 (对照组 )。采用酶法测定治疗前后的总胆固醇 (TC)、甘油三酯 (TG)、高密度脂蛋白胆固醇 (HDL C)等的变化 ,应用酶联免疫吸附试验法测定氧化低密度脂蛋白 (oxLDL)治疗前后的变化。结果 :中药降脂通脉口服液可明显改善多种脂质成分 ,阻止低密度脂蛋白氧化。结论 :降脂通脉方对高脂血症有一定的治疗作用 。Objective:To observe the therapeutic effect of Jiangzhitongmaifang(JZTMF)in treating Hperlipideproteinemia(HLP). Method:61 patients with HLP were randomly divided into two group:JZTMF theraputic group, Lovastating control group.The level of plasma TC、TG and HDL were measured by zymic method. The level of plasma oxLDL were measured by ELISA. Results:After using JZTMF the level of plasma TC、TG、LDL and AI、apoB clearly went down. JZTMF could inhibit LDL from being oxidized. Conculsion:JZTMF has theraputic value for HLP and prevents AS improvement.

关 键 词：降脂通脉方 高脂血症 血脂 氧化低密度脂蛋白 

分 类 号：R285.6[医药卫生—中药学]