心理行为干预对乳腺癌患者情绪反应及免疫功能的影响  

THE EFFECT OF PSYCHO-BEHAVIORAL INTERVENTIONON THE EMOTIONAL REACTION AND IMMUNE FUNCTIONIN BREAST CANCER PATIENTS UNDERGOING RADIOTHERAPY

作　　者：刘艳[1] 林文娟[1] 刘新帆[2] 张冀岗[2] Erika M Hardy Meg Mountainbear 

机构地区：[1]中国科学院心理研究所脑-行为研究中心 [2]中国医学科学院肿瘤医院 [3]Michigan University,Ann Arbar MI48109,USA

出　　处：《心理学报》2001年第5期437-441,共5页Acta Psychologica Sinica

基　　金：中国科学院创新项目 (KSCX2 -2 -0 3) ;国家自然科学基金项目 ( 39770 2 6 5 ;39830 130 )

摘　　要：按随机和匹配原则 ,将 40名乳腺癌放疗患者分入干预组和对照组。对干预组患者进行为期 4周的心理行为干预 ,对照组仅接受相应的医药治疗。以肿瘤病人情绪适应问卷 (MAC)和免疫测试法研究患者干预前后的情绪反应和免疫功能 ,探讨心理行为干预对乳腺癌患者情绪反应和免疫功能的影响。结果发现 ,心理行为干预有利于提高患者NK细胞活性 (NKCA) ;并有助于维持放疗期间患者的白细胞水平。Matched on a series of demographic and medical treatment variables, forty hospitalized breast cancer patients undergoing radiotherapy were randomly assigned to either a psycho-behavioral intervention group or a control group. The 4-week intervention primarily consisted of multiple sessions of muscle relaxation exercises and guided imagery treatment. The results showed that the level of NK cell activity of the intervention group was significantly higher than that of the control group. The number of patients in the intervention group who had to use medicines to increase white blood cells during radiotherapy was significantly fewer than that of the control groups. No significant differences were found between these two groups in a set of emotional adjustment questionnaires. These results suggest that the intervention helped in strengthening patients' immune functioning but not in changing their emotional state..

关 键 词：乳腺癌 心理行为干预 情绪反应 免疫功能 

分 类 号：B845[哲学宗教—心理学]