新生儿TSH测定与成人尿碘测定的对比  

Neonatal TSH and adult urine iodine excretion in IDD monitoring

作　　者：李金炬[1] 翟俊山[1] 李均林[1] 刘连杰[1] 范琳燕[1] 吕建国[2] 王秀文 

机构地区：[1]沈阳市地方病防治所 [2]中国地方病防治研究中心地甲所 [3]新民县卫生防疫站

出　　处：《中国地方病学杂志》1993年第3期129-131,共3页Chinese Jouranl of Endemiology

摘　　要：本文报道了用纸片法测定沈阳碘缺乏病区新生儿 TSH6498人,结果显示亚临床甲低人群占11.9%,与尿碘测定显示结果12.0%是一致的。进一步比较各县区新生儿 TSH 值与成人尿碘值,发现二者之间成高度负相关,且有较好的直线回归关系。笔者对两种测定方法做了简单对比,认为新生儿纸片TSH 测定是碘缺乏病监测的可靠指标,建议在我国逐步推广应用。This paper describes a comparative studyon neonatal TSH IRMA on blood spot andadult urine iodine excretion for their uses inIDD monitoring,with 6498 neonatal heel-prickblood and 1663 adult urine samples tested,which were collected,respectively,from differ-ent iodine deficiency areas around Shenyang,where have been covered with iodine prophy-laxis for years.The data of neonatal TSH test,judging from the frequency distribution at dif-ferent levels,showed that 11.9% of the testswere found with TSH values over 10 uIU/mlwhich was taken as the normal reference cut-off point,it is in accordance with the loweredurine test result of 12%.And a negative corre-lation between the two tests was found.Inconclusion,it is suggested that neonatal TSHIRMA on blood spot,in terms of its sensitivityand validity,be an ideal monitoring indicatorof IDD monitoring and should be widely usedby recommendation.

关 键 词：新生儿 TSH 成人 尿碘 甲减 

分 类 号：R722.190.4[医药卫生—儿科]