超细纤维支气管镜及肺灌洗技术在尘肺检查中的应用  

Use of Ultrathin Fiber bronchoscope and BAL in Patients with Pneumoconiosis

作　　者：李德鸿[1] 卢世璇[1] 张翠娟[1] 袁岚[1] 陈宁蒙[1] 邹昌淇[1] 刘菱芬[1] 张金松[1] 周晓燕[1] 王文举 

机构地区：[1]中国预防医学科学院劳动卫生与职业病研究所,100050 [2]中国统配煤矿职业医学研究所

出　　处：《中国工业医学杂志》1993年第3期130-133,共4页Chinese Journal of Industrial Medicine

摘　　要：本研究对58例有粉尘接触史工人及7名志愿者进行了纤维支气管镜检查及支气管肺泡瘤洗,其中22例进行了超细纤维支气管镜检查。普通纤维支气管镜部分病例可见支气管粘膜充血肿胀,有的可见支气管粘膜苍白、无光泽等改变。支气管分叉处常见色素沉着斑,以接触煤尘者为著。个别晚期尘肺病例可见支气管严重扭曲变形、管腔狭窄或不规则。22例超细纤维支气管镜检查见15例(68.2％)有色素沉着,其次为粘膜充血,多为弥漫性。5例见周围气道粘膜苍白。支气管肺泡灌洗液检查见接尘组细胞总数和细胞浓度最高。Fn测定在接尘组和尘肺观察对象组最高。TBLB可见远端组织典型尘肺样改变。58 workers with a history of exposure to various mineral dusts and 7 volunteers wereexamined by fiberbroncnoscope and lavage.Among them, 22 were examined by ultrathinfiberbroncnoscope. During convential BF, insome cases, the bronchial mucosa showedcongestion and edema, in some cases, thebronchial mucosa was pale in colour, no lus-ter on its surface. At the bifurcation of bro-nchi, small patchy black or brownisn pigme-ntation could be seen, more in coal workers.In cases of more advanced pneumoconiosis,lumen was distorted and stenosed or irregul-ar in contour. Under BFT examination,15(68.2%)had pigmentation in small airways.Congestion of mucosa in small airway mi-ght be diffuse. 5 showed pale of bronchialmucosa. In BALF, total cell count and cellconcentration were highest in workers onlywith exposure history. Fn in workers onlywith exposure history and workers with 0^+diagnosis of pncumoconiosis were significantlyhigner than in control. TBLB showed thattypical pathologic lesions of pneumoconiosiscould seen in terminal lung tissue.

关 键 词：尘肺 肺灌洗 纤支镜检 

分 类 号：R598.204[医药卫生—内科学]