雪山芪的化学成分研究  

Studies on chemical constituents of Hedysarum sikkimense var. rigidum

作　　者：李云森[1] 陈纪军[1] 廖心荣[1] 王惠英[1] 罗士德[1] 

机构地区：[1]中国科学院昆明植物研究所,云南昆明650204

出　　处：《中草药》2001年第6期489-490,共2页Chinese Traditional and Herbal Drugs

摘　　要：目的　研究雪山芪 H e dysaram sikkimense Benth.ex Baker.var.rigidum Hand.- Mass.的化学成分。方法　采用反复硅胶柱层析分离纯化 ,通过理化常数测定和光谱分析鉴定化合物的结构。结果　从雪山芪干燥根中分离得到 9个化合物。根据波谱分析和理化数据 ,鉴定出其中 8个化合物分别为 :羽扇豆醇 (lupeol, )、4′-羟基 - 7-甲氧基异黄酮 (isoform ononetein, )、4′-羟基 - 6 ,7-二甲氧基异黄酮 (3- [4- hydroxyphenyl- 6 ,7- dimetoxy- 4H- 1- ben-zopyran- 4- one], )、熊果酸 (ursolic acid, )、山嵛酸 - α-单甘油酯 (docosanooic acid- 2 ,3- dihydroxypropyl ester, )、二十四烷酸 (lignoceric acid, )、β-谷甾醇 (β- sitosterol, )及蔗糖。结论　以上化合物均为首次从该植物中分得。Object To study the chemical constituents of Hedysarum sikkimense Benth. ex Baker var rigidum Hand Mazz Methods The constituents were repeatedly separated and purified on silica gel column They were identified and structurally elucidated by physicochemical data and spectral analysis Results Nine compounds were obtained Eight of them were lupeol (Ⅰ); isoformononetein (Ⅱ); 3 (4 hydroxyphenyl) 6,7 dimethoxy 4H 1 benzopyran 4 one (Ⅲ); ursolic acid (Ⅳ); docosanoic acid 2,3 dihydroxypropyl ester (Ⅴ); lignoceric acid (Ⅵ); β sitosterol (Ⅶ) and sucrose (Ⅷ) Conclusion All of them are isolated from this plant for the first time

关 键 词：雪山芪 豆科 异黄酮 三萜 

分 类 号：R284.1[医药卫生—中药学]