HBsAg阳性血清HBV-DNA定量与肝功能指标的相关性分析  

Analysis on Correlation Between Quantitative HBV-DNA and Liver Function in HBsAg Positive Serum

作　　者：冉晓青 邓君[2] 杨朝国[3] 徐继华[4] 

机构地区：[1]攀枝花矿务局总医院,四川攀枝花617066 [2]四川省人民医院,四川成都610072 [3]四川省卫生管理干部学院,四川成都610041 [4]泸州市纳溪区妇幼保健院,四川泸州646300

出　　处：《四川省卫生管理干部学院学报》2001年第4期251-252,264,共3页Journal of Sichuan Continuing Education College of Medical Sciences

摘　　要：目的 :探讨乙型肝炎病毒复制水平是否与肝功能有关。方法 :对 71例HBsAg( +)血清用PCR -ELISA定量法测定HBV -DNA含量 ,同时进行肝功能 (ALT、AST、ALT/AST、TBIL、DBIL、IBIL)测定。结果 :在 5 3例HBV -DNA阳性血清中 ,ALT在 40u/L以内居多 ,余 18例HBV -DNA阴性血清中肝功能异常者比例有所增高。结论 :经散点图分析 ,乙型肝炎病毒DNA含量与六项肝功能指标既无直线相关关系 ,也无曲线相关关系。Objective:To Probe the correlation between replication of HBV-DNA and liver function. Methods:71 positive HBsAg serum cases were measured the content of HBV-DNA by using quantitative PCR-ELISA, and ALT?AST?ALT/AST?TBIL?DBIL?IBIL were also tested at the same time.Result: Most of HBV-DNA positive serum cases,ALT were lower than 40 U/L, In 18 HBV-DNA negative serum cases,the ratio of abnormal liver function showed an increasing trend. Conclution: By analysis of scattered dots map,there have not the correlation between the HBV-DNA and liver function.

关 键 词：乙型肝炎病毒核酸 聚合酶链反应 肝功能试验 

分 类 号：R446.6[医药卫生—诊断学]