急性心肌梗塞静脉溶栓再通的临床指征与冠状动脉造影的对比研究  

A Comparative Study of Clinical Predictors and Coronary Atery Angiography after Intravenous Thrombolytic Therapy

作　　者：郭静萱[1] 毛节明[1] 郭丽君[1] 李海燕[1] 葛堪忆[1] 陈明哲[1] 

机构地区：[1]北京医科大学附属第三临床医院,100083

出　　处：《中国心血管杂志》1996年第1期21-23,共3页Chinese Journal of Cardiovascular Medicine

摘　　要：对100例急性心肌梗塞患者行静脉溶栓治疗,以冠状动脉造影结果为标准,探讨参考方案及临床指征判定冠脉再通的价值及意义.结果:参考方案的敏感性为91.8%,特异性为70.6%,临床准确度为81.0%.说明参考方案与冠状动脉造影有很好的相关性,判定冠状动脉再通的准确性很高.在各项临床指征中,酶峰值提前的特异性最高.溶栓后≤1小时终末T波倒置可单独做为极早期判定冠状动脉再通的指征.Obsjective: To assess the accuracy of clinical criteria in assessing treatment. Methods: Coronary angiography was performed inorder to comparatively evaluate predictions based on clinical parameters alone. One hundred(100)patients were involved in this study. Result:Clinical determinants showed a 91. 8% sensitivity, 70. 6% specificity and 81% predictive accuracy for coronary recanalization prediction. This result indicates that clinical parameters are strongly correlated to the coronary angiography and are strongly predictive for patency of an infarct-related vessel. Of all these parameters,the early peak of cardiac enzymes levels had the highest specificity. T-wave inversion within one hour after thrombolytic therapy can be used alone as an earlier sign of coronary recanalization.

关 键 词：临床指征 冠状动脉造影 冠状动脉再通 静脉溶栓 急性心肌梗塞 对比研究 特异性 意义 准确性 判定 

分 类 号：R542.22[医药卫生—心血管疾病] R541.4[医药卫生—内科学]