硝基甲烷对人体慢性危害的探讨  

Study on Chronic Hazard of Nitromethane to Human Body

作　　者：白汝义[1] 李忠[1] 贾明德[1] 曹德文[1] 游全程[2] 程崇泉[2] 薛素琼[2] 黄瑞文[2] 文必昌[2] 孙秀丽[2] 尚家芸[2] 刘宣伟[3] 胡成瑞[3] 郭志伟[3] 

机构地区：[1]沈阳市劳动卫生职业病研究所 [2]华西医科大学附属职业病防治院 [3]四川国营沪州化工厂工业卫生科

出　　处：《中国工业医学杂志》1991年第3期14-15,M002,共3页Chinese Journal of Industrial Medicine

摘　　要：通过流行病学调查,发现较长时期接触低浓度硝基甲烷(1.3～27.4mg/m^3)作业工人,可引起轻度神经衰弱症候群及粘膜刺激症状。并且硝基甲烷作业工人的红细胞、血红蛋白、碱性磷酸酶、胆碱酯酶增高,血清三碘甲状腺原氨酸(T_3)降低。上述改变可作为长期接触硝基甲烷的生物学监测指标。90 workers who have exposed to nitromethane for 1～10 years were investigated inthe study. The results showed that theworkers with long-term exposure to nitrom-ethane of low concentation (1.3～27.4mg/m^3)had mild neurasthenic and mucosal stimulation.The levels of RBC and Hb and the activi-ties of AKP and ChE were increased. The seru-m level of T_3 was significantly decreaced. It seemed that these changes might beused as biomonitoring indices for the workersof nitromethane.

关 键 词：慢性危害 作业工人 人体 轻度 MG/M^3 长期接触 刺激症状 硝基甲烷 降低 低浓度 

分 类 号：R135[医药卫生—劳动卫生] R163[医药卫生—公共卫生与预防医学]