小剂量阿替洛尔治疗心衰的疗效观察  

Effect of Small Dose of Atenolol on Heart Failure

作　　者：郭晓玲[1] 马国珍[1] 涂毅萍[1] 

机构地区：[1]包头医学院第一附属医院揗环内科,内蒙古014010

出　　处：《解剖与临床》1997年第4期163-164,共2页Anatomy and Clinics

摘　　要：采用自身对比法对阿替洛尔治疗16例心衰患者疗效进行观察,其中缺血性心肌病11例,扩张型心肌病5例。心功能Ⅱ、Ⅲ、Ⅳ级分别为4例、8例和4例。在强心、利尿、血管扩张剂基础上加用阿替洛尔6.25mg/次,每日2次,3天后剂量加倍。心功能Ⅱ、Ⅲ级患者用药后显效5例,有效7例。用药后收缩压和舒张压下降,心率减慢,心功能改善由用药前3±0.75级降至1.93±1.34级,射血分数增加。阿替洛尔对缺血性心肌病和扩张型心肌病心功能Ⅱ、Ⅲ级患者有治疗作用。Self-comparative method was used to observe the effect of Atenolol on 16 patients with heart failure, of whom 11 were with ischemic heart disease, 5 dilated cardiomyopathy. 4 of the patients were in grade Ⅱ heart function,8 in grade Ⅲ and 4 in gradeⅣ -The patients were given Atenolol 6.25mg,2 times a day in addition to Digitalis, Diuretic and Vasodilator and Atenolol dose was doubled 3 days later.The results showed that Atenolol had obvious effect 5 patients and effect on 7 patients .With grade Ⅱ and Ⅲ heart function after treatment, SBP and DBP decreased; heart rate slowed down; heart function improved from grade 3 ±0.75 to grade 1 .93 ± 1.34,and LVEF increased as well. It was concluded that Atenolol had effect on patients with ischemic heart disease and dilated cardiomyopathy in grade 2222 and 3333 heart function.

关 键 词：治疗 阿替洛尔 心功能改善 心衰 缺血性心肌病 扩张型心肌病 小剂量 疗效观察 心率减慢 用药后 

分 类 号：R541[医药卫生—心血管疾病] R542[医药卫生—内科学]