正交试验法优选甲芪肝纤颗粒中防己醇提工艺的研究  

Optimum extraction of radix stephaniae tetrandrae from Jiaqiganxian granules by orthogonal design

作　　者：谢安 

机构地区：[1]湖南九芝堂股份有限公司,长沙410008

出　　处：《中南药学》2004年第1期27-28,共2页Central South Pharmacy

摘　　要：目的 以粉防己碱为含量指标,研究甲芪肝纤颗粒中防己的醇提工艺。方法 采用正交试验设计进行优选,分光光度法测定粉防己碱含量。结果 乙醇浓度对粉防己碱提取有显著性影响(P<0.05)。结论 最佳提取工艺为:90％乙醇回流提取2次,每次1h。OBJECTIVE To study the extraction of the tetrandrine from Jiaqiganxian granules. METHODS The optimum extraction was selected by orthogonal design. The content of total tetrandrine was determind by spectrotho-tometry. RESULTS The concentration of alcohol significantly influenced the total tetrandrine. CONCLUSIONS The optimum extraction is as follows: adding 90% ethanol into Stephania tetrandra S. Moore medical materials, extracting by relux for 1 h each time, and extracting twice.

关 键 词：甲芪肝纤颗粒 正交试验 粉防己碱 分光光度法 

分 类 号：R943[医药卫生—药剂学]