测定血清肿瘤坏死因子在急性危重病中的临床意义  

Serum tumor necrosis factor in patients with acute critical illness:Clinical significance

作　　者：李春盛[1] 朱丽楠[1] 蒋瑞英[1] 赵卉[1] 高秀兰[1] 贾凤兰[2] 武珊珊[2] 张晓红[2] 

机构地区：[1]北京军区总医院急诊科,100700 [2]北京军区总医院肝病研究所,100700

出　　处：《中国危重病急救医学》1993年第4期218-219,共2页Chinese Critical Care Medicine

摘　　要：测定了54例急性危重病患者和21例正常人血清肿瘤坏死因子水平。结果表明:血清肿瘤坏死因子在急性心肌梗塞组(26.40±19.74U/ml)、脑卒中组(18.25±4.94U/ml)和心衰组(38.57±48.18U/mkl)均较正常对照组(15.80±1.70U/ml)升高(P<0.05)。在54例危重患者中有7例血清肿瘤坏死因子明显升高。作者认为危重病患者血清肿瘤坏死因子升高与病变的严重程度、有无并发症和感染有关。Serum tumor necrosis factor(TNF)was deter-mined in 54 patients with acute critical illness and 21normal controls.Serum TNF in acute myocardialinfarction(AMI)group(26.4±19.74U/ml),acutestroke group(18.25±4.94 U/ml)and congestiveheart failure groun(38.57±48.18)was significantlyhigher than in the control group(P<0.05).SerumTNF was markedly increased in 7 of the 54 patients.We consider that the elevation of serum TNF in pa-tients with critical illnes is related to the existence orinexistence of complications and infections.

关 键 词：肿瘤坏死因子 危重病 

分 类 号：R459.7[医药卫生—急诊医学]