牛骨形态发生蛋白—明胶—羟基磷灰石骨移植材料的研制及动物实验研究  

PREPARATION OF BOVINE MORPHO GENETIC PROTEIN—GELATIN—HY DROXYAPATITE AND ITS RELATED EXPERIMENTAL STUDY

作　　者：林松[1] 李东方[2] 徐印坎[1] 张文明[2] 陈泳莲[3] 周志华[1] 

机构地区：[1]上海第二军医大学长征医院骨科,200003 [2]上海第二军医大学化学教研室,200433 [3]上海第二军医大学长征医院病理科,200003

出　　处：《中国修复重建外科杂志》1993年第3期156-157,共2页Chinese Journal of Reparative and Reconstructive Surgery

摘　　要：对牛骨形态发生蛋白-明胶-羟基磷灰石(bBMP-G-HA),骨移植材料的研制及修复大鼠桡骨缺损的动物实验。结果表明bBMP-G-HA具有诱导成骨活性和可吸收性,显著增加骨缺损修复速度。Bovine bone morphogenetic proteingelatin-hydroxyapatite (bBMP-G-HA) was prepared and its efficacy in bone repair of the diaphyseal defects of radii of rats was studied. The results suggested that bBMPG-HA was osteogenetic and capable of being resorbed, and might be used clinically as a new substitute for bone graft.

关 键 词：骨形态发生 蛋白 羟基磷灰石 

分 类 号：R318.08[医药卫生—生物医学工程]