缺血性心律失常机制的电生理实验研究  

ELECTROPHYSIOLOGIC STUDY ON THE MECHANISM OF ISCHEMIC ARRHYTHMIAS IN DOGS

作　　者：尹红[1] 张薇[1] 王子法[1] 张运[1] 刘旭[1] 张振杰 

机构地区：[1]山东医科大学附属医院心内科 [2]山东省莱芜市城关镇医院内科

出　　处：《中国循环杂志》1993年第4期221-222,共2页Chinese Circulation Journal

摘　　要：本文在20只狗实验性缺血时,应用心电活动三维标测系统,对心肌“多层次双极针电极”进行电生理检查。结果表明,86%的缺血性心律失常起源于缺血区心内膜下,与缺血心肌发生延迟激动、分裂电活动及连续电活动有关,支持壁内折返机制。14%的心律失常起源于再灌注区的正常交界处的心内膜下,未记录到分裂电活动及连续电活动,支持非折返机制。Twenty dogs of experimental ischemia were studied with a three dimensional mapping system of cardiac electrical activity and multiple-level myocardial recordings by bipolar plunge-needle electrodes. 86% of theischemic arrhythmias (IA) initiated in the ischemic subendocardium were associated with delayed fragmented activity and continuous electrical activity in accordance with intramural reentry. 14% of IA initiated in the subendocardium of the normal junction zone in the reperfused zone and multiple-level myocardial recordings showed that there was no fragmented activity and continuous electrical activity in accordance with a nonreentrant mechanism.

关 键 词：缺血性 心律失常 

分 类 号：R541.7[医药卫生—心血管疾病]