肽能神经在新生儿及无肛畸形儿直肠远端肠壁内的分布  

The Distribution of the Peptide Nerves on the Distal Rectal Wall of Normal Newborns and Pediatric Imperforate Anus

作　　者：王伟[1] 李正[2] 王之章[3] 王练英[2] 姜卫国[3] 

机构地区：[1]中国医科大学附属第二医院小儿外科 [2]中国医科大学附属第二医院小儿外科 [3]中国医科大学病理科

出　　处：《中国医科大学学报》1993年第5期374-377,共4页Journal of China Medical University

基　　金：国家自然科学基金

摘　　要：本实验结果显示,无肛畸形儿直肠盲端肠壁各层SP能阳性神经纤维、粘膜下神经丛、肌间神经丛及神经节细胞数均较新生儿明显减少,并且阳性神经免疫反应强度减弱。提示该畸形有明显的SP能神经组织发育不全。The distribution of SP peptidt nerves of distal rectal segment was studied by means of immunohistochemical technique ABC procedure. The number of SP-positive fibers in all layers of rectal wall and ganglionic cells as well as the plexus in both mysenteric and Sub-mucosal plexus were comparatively few in imperforate anus than that in newborns, and the intensity of SP-positive reaction was also very weak in impertorate anus cases. This study suggests that the anorectal deformity is accompanied with obviously SP peptide nervous tissues malformation.

关 键 词：无肛畸形 P物质 免疫组织化学 

分 类 号：R726.2[医药卫生—儿科]