计算机控制给药系统的设计与临床应用  

Design and clinical application of computerized control system for drug titration

作　　者：吴穷[1] 王湘生[1] 李佳春[1] 李功宋[1] 江朝光[1] 

机构地区：[1]解放军总医院

出　　处：《中国医疗器械杂志》1993年第3期137-141,146,共6页Chinese Journal of Medical Instrumentation

摘　　要：本文根据血压的数学模型,建立了一个血压的多模型自适应控制系统。在实际应用中,系统通过血压的实时反馈大小以及对病人血压变化情况的在线辨识,选择相应的PID控制器,从而自动确定出最为适宜的硝普钠滴入速度。30例的临床应用结果表明,使用该自动给药系统能够较好地保持灌注压的平稳。A computer-based feedback system is designed that regulates the infusion rate of vasodilator (sodium nitrop usside, SNP) with instantaneous mean arterial pressure response. A set of alter-gain reference models related to blood pressure is included in the algorithm, and multiple model adaptive control procedures have been considered.Corresponding proportion-plus-integral controller is selected to achieve steady -state and transient specifications through on-line identification for mean arterial pressure. Our preliminary application in 30 cases yields satisfactory results with demonstration of the robustness of this multiple-model controller.

关 键 词：计算机 给药系统 设计 临床应用 

分 类 号：R654.108[医药卫生—外科学]