槲寄生抗心律失常作用的细胞电生理研究  

STUDY OF ANTIARRHYTHMIC ACTION OF VISCUM COLORATUM ON CELLULAR ELECTROPHYSIOLOGY

作　　者：吴继雄[1] 俞国瑞[2] 王彬尧[1] 黄定九[1] 

机构地区：[1]安徽医科大学附一院心内科,合肥230022 [2]上海第二医科大学附属仁济医院心内科,上海200002

出　　处：《中国医药工业杂志》1993年第10期457-460,共4页Chinese Journal of Pharmaceuticals

摘　　要：用玻璃微电极及选择性膜通道阻滞剂观察了槲寄生注射液对离体狗心脏浦氏细胞及豚鼠心室肌细胞快反应动作电位的影响。结果表明槲寄生能加速动作电位复极进程,使ERP/APD比值增加,不应期相对延长,该作用与抑制细胞膜I_(si)及增加I_x有关。The effects of Viscum coloratum on the fast response action potentials of canine Purkinje's fibers and guinea pig papillary muscles were studied by glass-micro-electrode technique and selective ion blockers in vitro. It is suggested that Viscum coloratum accelerates the repolarization of fast action potential, increases ERP/APD ratio and prolongs relatively ERP by inhibiting I_(si) and increasing I_x.

关 键 词：槲寄生 电生理学 心律失常 

分 类 号：R282.710.5[医药卫生—中药学]