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作 者:刘保平[1] 沈霖[1] 杨家玉[1] 杨艳萍[1] 高兰[1]
机构地区:[1]同济医科大学附属协和医院骨伤科研究室,武汉430022
出 处:《中国中西医结合杂志》1993年第4期215-216,共2页Chinese Journal of Integrated Traditional and Western Medicine
摘 要:本研究动态观察了中西医结合疗法对清创术后C-反应蛋白的影响,并与单纯西药组进行了对照。结果表明:治疗4天后两组的C-反应蛋白均呈下降趋势,但中西医结合组下降幅度更大,两组相比,P<0.01;治疗1周后,中西医结合组C-反应蛋白恢复正常,而西药组仍高于正常范围,P<0.001。说明中西医结合疗法在影响C-反应蛋白水平、降低感染率方面明显优于单纯西药疗法。提示清创术后患者在常规应用抗生素的同时,加服某些具有调节机体免疫功能的中药,可提高临床疗效。C-反应蛋白可作为判断清创术后是否继发感染及某些药物疗效的可靠客观指标。Closely monitoring whether the secondary infection in the patients of post-debridement occurredor not and appropriately treating these patients were the important ways to reduce the incidence ofinfection. Through estimating the level of the serum C-reactive protein (CRP) as the monitoringindex of infection, dynamically observed the effect of the combined traditional Chinese and Westernmedicine therapy (TCM-WM) on CRP after debridement, as was compared with the effect of theWestern medicine therapy (WM) group in which only the WM was administrated. The result showedthat the levels of CRP decreased in both TCM-WM and WM group on 4th day after the operation,but the level of CRP in former group was lower than that in latter one, the difference was verysignificant (P<0.001). So that, it was assumed that TCM-WM significantly excelled the WM onaffecting the level of CRP and reducing the incidence of infection. It was snggested that CRP couldbe used as an effective and objective index to determine whether the secondary infection hashappened and to assess the efficacy of some drugs.
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