甲状腺功能减退症与肾阳虚关系探讨  

Study on Relationship of Hypothyroidism and Deficiency of Kidney Yang

作　　者：查良伦[1] 沈自尹[1] 张萍 

机构地区：[1]上海医科大学中西医结合研究所,上海200040

出　　处：《中国中西医结合杂志》1993年第4期202-204,共3页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：用补肾中药参鹿片治疗32例甲状腺功能减退症患者1年,其中17例并用小剂量甲状腺片,临床症状及甲状腺功能明显好转,红细胞钠含量降低,细胞膜对钠的通透性及钠泵活性明显升高,治疗前后差异均有显著意义。提示甲状腺功能减退症与肾阳虚及能量代谢有密切关系。32 cases of hypothyroidism caused by various factors were treated for one year withChinese medicinal herbs preparation 'Shen Lu tablet' (参鹿片,SLT) to warm and reinforce theKidney Yang. 34 normal persons were studied as a control group. After treatment with SLT, theclinical symptoms of hypothyroidism were markedly improved. Average serum concentration oftotal T3, T4 increased significantly from 67.06±4.81 and 3.29±0.42 before treatment to 120.50±6.34ng/dl and 6.31±0.38μg/dl, respectively (P<0.001). Serum levels of TSH decreased evidentlyfrom 20. 81±2.78 before therapy to 3.32±0.61ng/ml (P<0.001). Before treatment with SLT, hypoth-yroidism group had hlgher erythrocyte sodium content ([Na]_(Rbc)) than that of normal group. Thepermeability of the cell membrane ~oM_(Na)^(os) and the activity of sodium pump ~oK_(Na)^(os)in intact erythrocyteswere markedly lower in the treated group than that in the normal group. In hypothyroidism patientstreated by SLT the [Na]_(Rbc) significantly dropped, and the ~oN_(Na)^(os)and ~oK_(Na)^(os)were significantly raisedwhen compared with those before treatment, P<0.001. It is suggested that hypothyroidism wasclosely related with Deficiency of Kidney Yang and energy metabolism.

关 键 词：参鹿片 肾阳虚 甲减 

分 类 号：R581.2[医药卫生—内分泌]