加味玉屏风散对老龄小鼠微循环及血浆SOD活力影响的实验研究  

Experimental Study on Effect of Jiawei Yupingfeng San on Microcirculation and Plasma SOD Activity of Old Mice

作　　者：李超英[1] 靳红微[1] 耿延[1] 甄彦君[1] 阎明 凌亦凌[2] 戴桂满[1] 薛芳[1] 崔志永[1] 马银霞[3] 李永谦[3] 

机构地区：[1]河北中医学院,石家庄050091 [2]河北医学院 [3]河北医学院附属第三医院

出　　处：《中国中西医结合杂志》1993年第7期426-427,共2页Chinese Journal of Integrated Traditional and Western Medicine

摘　　要：为探讨加味玉屏风散调节'肺主治节'功能以及延缓衰老的机制,本文对服用该方的老龄小鼠微循环及血浆超氧化物歧化酶(SOD)活力、丙二醛(MDA)含量及血色素(Hb)、红细胞(RBC)含量等进行了观察。现报告如下。实验材料一、药物组成加味玉屏风散生药饮片黄芪、白术、防风、麦冬等按常法水煎浓缩至含0.42%生药汁备用。二、动物 15月龄健康昆明种小鼠100只,体重38～52g,雌雄各半,由河北医学院动物科提供。方法与结果一、给药方法将小鼠随机分为服药组与对照组,均以常规饲料喂养。The effects of Jiawei Yupingfeng San on microcirculation and plasma SOD of old mice wereobserved. The results showed that the prescription could markedly improve old mice's blood flow ofmicrocirculation, increase their speed of blood flow and raise their plasma TSOD and Cu, Zn-SODactivity, and there was very significant difference compared with control (P<0.001). The resultssuggested that this prescription had the effects of improving the quality of life and delaying the agingof organism.

关 键 词：玉屏风散 小鼠 微循环 丙二醛 

分 类 号：R289.5[医药卫生—方剂学]