复方固环止血冲剂药效学研究  

PHARMACOLOGICAL STUDY OF COMPOUND GUHUANZHIXUE GRANULE

作　　者：张金妹[1] 高凤辉[1] 孙红[1] 李连达[1] 李明章 王升辉 

机构地区：[1]中国中医研究院西苑医院基础研究室,北京100091 [2]辽宁辽阳制药厂,辽阳111000

出　　处：《中药新药与临床药理》1993年第1期31-35,共5页Traditional Chinese Drug Research and Clinical Pharmacology

摘　　要：固环止血冲剂不同剂量,对大鼠正常子宫平滑肌收缩有明显抑制作用,并可对抗由催产素引起的子宫平滑肌强烈收缩。对动物子宫内异物多种炎症模型有明显的抗炎作用,该方尚有缩短出血和至凝血时间的作用。提示该方具有对育龄妇女上避孕环后的止血、止痛、抗炎等功效。The pharmacodynamics of compound Guhuanzhixue granule(CGH- ZX)was studied.The results showed that CGHZX inhibited the contraction of rat's uterine smooth muscle and antagonized the vigorous contraction induced by oxytoxin in vitro,It exerted an anti-inflammatory effect in rats and miee with uteritis caused by various foreign bodies,This preseription also shertened the bleeding and coagulation times in mice.It is suggested that CGHZX is applicable to metrorrhagia,pain and uteritis occurring after setting of contra- ceptive ring.

关 键 词：固环止血冲剂 药理学 止血 止痛 

分 类 号：R285.5[医药卫生—中药学]