坤泰安的主要药效学研究  

A STUDY ON THE MAIN PHARNACODYNAMICS OF KUNTAIAN

作　　者：张金妹[1] 孙红[1] 高凤辉[1] 李连达[1] 王秉岐 李耀华 

机构地区：[1]中国中医研究院西苑医院基础研究室,北京100091 [2]山西神池制药厂,山西神池036100

出　　处：《中药新药与临床药理》1993年第3期26-29,共4页Traditional Chinese Drug Research and Clinical Pharmacology

摘　　要：对中药复方“坤泰安”进行了药效学实验研究。结果表明,给予坤泰安不同剂量对正常子宫平滑肌收缩有不同程度的抑制作用,有明显对抗由催产素引起的子宫平滑肌强烈收缩,对幼年大鼠生殖器官发育有一定促进作用。并可促进毛细血管开放,增加血流速度和改善流态。还有镇痛、抗炎及消肿作用,提示该方可用于治疗妇科痛经、月经不调及妇科炎症等疾病。The pharmacoclynamics of Kuntaian was studied. The results showed that it exerts an inhibiting effect on normal uterine smooth muscle in a dosedependent manner. It can counteract the violent uterine contraction induced by pituitrin, promote the growth of uterus of young mice, dilate the capilaries and accelerate blood circulation. It also exerts analgesic antiphlogistic antioneotie effects, suggesting that this drug may be applicable to the treatment of dysmanorrhea, irregular menstruation and pelvic infection.

关 键 词：坤泰安 药理学 止痛 痛经 

分 类 号：R285.5[医药卫生—中药学]