小剂量X射线诱发雄性小鼠生殖细胞染色体畸变与显性致死间关系  

Relationship between chromosomal aberration of germ cells and dominant lethal mutation in male mice after low dosage of X-irradiation

作　　者：王明东[1] 杨宝辰[1] 金玉珂[1] 

机构地区：[1]白求恩医科大学放射医学研究所遗传研究室

出　　处：《白求恩医科大学学报》1989年第1期19-22,共4页Journal of Norman Bethune University of Medical Science

摘　　要：本文报道了小剂量(0～1.0 Gy)x射线单次全身照射雄性小白鼠诱发的精母细胞晚粗线期染色体畸变与显性致死间关系。证明畸变细胞率与胎仔死亡率间相关,但后者均是前者的2.5倍。X射线在该期诱发的显性致死突变率是2.1995×10^(-3)/(配子·10mGy)。The relationship between chromosomal aberration and dominant mutation in spermatocytes of late pachytene phase in male mice after a single X-irridiation was reported. It was found that the frequency of aberrant cells was correlative to the rate of fetal death, the latter was being about 2.5 times as high as the former. The frequency of dominant lethal mutation induced by X - irradiation is 2.1995×10-3gamete·10mGy.

关 键 词：X线 生殖细胞 染色体 畸变 致死 

分 类 号：Q274[生物学—细胞生物学]