中药预防性治疗母婴血型不合  

The use traditional Chinese herb medicin in the prevention of maternal-fetal blood group incompatibility

作　　者：徐蕴华[1] 边旭明[1] 钱美伦[1] 刘善英[1] 盖明英 杨剑秋[1] 吴玉珍[1] 葛秦生[1] 

机构地区：[1]北京协和医院妇产科,100730

出　　处：《生殖医学杂志》1993年第4期203-206,共4页Journal of Reproductive Medicine

摘　　要：总结我院近20年来母婴血型不合112例(ABO 91例,Rh 21例)服用中药新溶Ⅰ号的临床效果。112例分为服药组(研究组)74例,对照组38例。结果表明预防服药明显降低了围产儿死亡率,服药组围产儿死亡率为14‰,对照组105‰,死亡病例均发生在 Rh 血型不合组,其中服药组围产死亡率77‰,对照组为500‰。此药能减轻溶血程度,ABO 血型不合服药组中重度溶血病例占6%,对照组为25%。Rh 血型不合服药组中重度溶血50%,对照组为80%。结果还表明服药期限与治疗效果相关,全部病例中服药期限>10周的重度溶血占12%,服药期限<10周占41%。中药对母血清免疫抗体效价在整个孕期没有升高或有不同程度下降。目前分析表明本药不但对预防 ABO 母婴血型不合有效,而且对 Rh 母婴血型不合也同样有预防性治疗效果。中药新溶Ⅰ号服用方便,无副作用,值得进一步深入研究。In 112 cases of maternal-fetal blood group incompatibility,ABO 91 cases and Rh 21cases all Chinese,have been studied after using traditional Chinese herb medicine (TCHM) for preventivetreatment.74 cases in the treatment group and 38 cases as control group,Preventive treatment withTCHM significantly reduced the perinatal mortality rate,treatment group 14‰ compare with controlgroup 105‰.Death cases were all in the Rh incompatibility,Rh treatment group 77‰ and control group500‰.The TCHM can also improve the degree of hemolysis.The severe cases in the ABO treatmentgroup it was 6%,while in the control group was 25% and in Rh cases it was 50% and control group80%.The duration of the drug use is closely related with the results of treatment.In all cases of use ofTCHM more than 10 weeks is 12% significantly better than those less than 10 weeks the severe cases is41%.The level of serum immuno-antibody (A and/or B) showed no increase but in the same cases mayshow a lower of titre.Present analysis showed that the TCHM is not only effective in ABOincompatibility but also good for Rh incompatibility.TCHM “Xin Rong No.1” is easy to take and noside effects but effective.Further research is worthwhile.

关 键 词：血型不合 中莓职法 新生儿溶血症 

分 类 号：R272.17[医药卫生—中医儿科学]