急性感染性疾病患者血清肿瘤坏死因子测定的临床意义  

Clinical Significance of Serum Tumor Necrosis Factor (TNF)Determination in Patients with Acute Infectious Diseases

作　　者：李春盛[1] 朱丽南 蒋瑞英[1] 赵卉[1] 贾风兰[2] 武珊珊[2] 张晓红[2] 

机构地区：[1]北京军区总医院急诊科,北京100700 [2]北京军区总医院肝病研究所,北京100700

出　　处：《急诊医学》1993年第2期69-70,共2页

摘　　要：测定了24例各种急性感染性疾病和21例正常人血清肿瘤坏死因子活性。结果发现,正常人血清肿瘤坏死因子均在正常范围内,而24例感染性疾病患者中有13例肿瘤坏死因子升高,认为各种急性感染性疾病发病初期的症状,如寒战,高热,食欲差等症状均与肿瘤坏死因子有一定的联系,即肿瘤坏死因子参与了炎症反应过程。Serum tumor necrosis factor (TNF)activity of 24 patients with acute infectious diseases and 21 normal healthy persons were measured in this study. The results showed that serum level of TNF was within normal range in the control group. However,serum level of TNF in 13 of 24 patients with acute infectious diseases were elevated. It suggests that symptoms and signs in the initial stage of acute infectious diseases such as rigors,fever and anorexia etc. may be related to high circulating TNF which may participate in the process of inflammation reaction.

关 键 词：感染性疾病 肿瘤坏死因子 血清 急性 炎症反应 

分 类 号：R510.2[医药卫生—内科学]