人胎胸腺实质内肥大细胞的观察  

MAST CELL IN THE PARENCHYMA OF THYMUS DURING THE DEVELOPMENT OF HUMAN FETUS

作　　者：张兰芬[1] 吴江声[1] 孙品伟[1] 郭杰[1] 陈慰峰[1] 

机构地区：[1]北京医科大学组织学与胚胎学系,北京医科大学免疫学系

出　　处：《北京医科大学学报》1994年第6期417-419,共3页Journal of Peking University(Health Sciences)

基　　金：国家自然科学基金和美国洛氏基金会中华医学基金

摘　　要：用长时间甲苯胺蓝，阿尔新蓝一番红花红二种组织化学方法，观察３～６个月人胎胸腺实质内肥大细胞的增殖与分化。结果表明，３个月胎时胸腺实质内仅有少数肥大细胞，随胎儿胎龄增长，胸腺实质内肥大细胞数量逐渐增多，大多数细胞位于皮质内，免疫组织化学法的观察证明，胸腺肥大细胞呈α１－抗胰蛋白酶阳性，α１－抗糜蛋白酶阴性，这表明胸腺肥大细胞属Ｔ肥大细胞（ＴＭＣ）型细胞。Two histochemical methods (long toluidine blue and alcian blue safranin staining)have been usedto observe proliferation and differentiation of the mast cell in the parenchyma of human fetalthymus,ranging from three to six months in gestation age.The results indicated that the number ofmast cells in the parenchymat of the thymus increased along with the development of human fetus.Most of the mast cells are in the cortex.The mast cells in the thymus were positive for α1-antitryp-sin,but negative for α1-antichymotrypsin by immunohistochemical method.This study suggests thatthe mast cells of human fetal thymus probably belong to trypsin positive mast cell(TMC).

关 键 词：肥大细胞 人胎胸腺 组织化学 免疫组织化学 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学] Q26[医药卫生—基础医学]