十种中草药体外抗细粒棘球绦虫原头节的实验研究  

In Vitro Cidal Effect 10 Chinese Traditional Herbs Against Echinococcus granulosus Protoscolices

作　　者：康金凤[1] 薛弘燮[1] 杨文光[1] 马新民[1] 姚志道[1] 邹培范 

机构地区：[1]新疆医学院寄生虫学教研室,新疆医学院一附院外科,新疆医学院一附院药剂科

出　　处：《地方病通报》1994年第3期22-24,共3页Endemic Diseases Bulletin

摘　　要：本文在体外培养条件下观察了仙鹤草、槟榔、山楂、鹤虱、苦楝皮、骆驼蓬、榧子、使君子、雷丸、南瓜子等１０种中草药对细粒棘球绦虫原头节的杀伤作用。其中骆驼蓬作用最强，在骆驼蓬浓度为０．２％的培养液中４８小时内原头节的校正死亡率达９０％。本文还在体外培养条件下观察到骆驼蓬杀虫有效成分—生物硷可透过棘球蚴囊壁；另用光镜和电镜观察到骆驼蓬作用主要破坏原头节的皮层和膜结构。his paper reports on the experimental results of the scolicidal effect of l0 Chinese herbs(Agrimonia,Areca,Crataegus,Fructus carpesii abrotanpidis,Melia azedarach,Peganum harmala,Torreya,Quisqualis,Om-phalia,Cucrbitae semina )against E. granulosus protoscolices in uitro. The Peganum harmala has stronger scolicidal effect than others。With 0.2%of this drug,the niortality rate of protoscolices reaches 90%in 48 houls。Its total alkaloids may pentrate hydatid cyst wall into hyddatid fluid and has scolicidal effect in hydatid fluid.Otherwise,observing by light microscopy and electron microscopy,the author found the damage to tegu-ment and membranous strtucture of protoscolices caused by this drug。

关 键 词：细粒棘球绦虫 原头节 中草药 

分 类 号：R285.5[医药卫生—中药学]