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作 者:闵志廉[1] 朱有华[1] 何长民[1] 贺宗理[1] 孟钢[1] 王卓伟[1] 齐隽[1] 王立明[1] 郑军华[1] 徐丹枫[1] 王亚伟[1] 任吉忠[1] 周梅生[1] 余加仁[1]
机构地区:[1]第二军医大学长征医院肾移植中心
出 处:《第二军医大学学报》1994年第5期401-406,共6页Academic Journal of Second Military Medical University
摘 要:1978年6月至1993年12月,我院共为969例慢性肾衰患者施行同种异体肾移植1011例次。人/肾总存活率:1年期为89.2%/78.7%;3年期为82.0%/74.7%;5年期为67.0%/58.4%;存活10年以上者已有12例。15年的肾移植经验表明:(1)提高肾存活率的因素是多方面的,其中高质量取肾与植肾手术尤为重要;(2)环孢素A等免疫抑制剂虽已普遍应用但仍应坚持ABO血型及淋巴细胞毒性试验配型工作;(3)感染仍是移植失败的重要原因,应将预防感染措施贯彻于术前、术中及术后全过程;(4)加强肾移植患者的随访工作,指导患者康复期的治疗,对肾移植后长期存活具有重要意义。renal allograft operations were performed in 969 chronic renal failure patients within 15 years,from June 1978 to December 1993. Patients/recipients survival rates were as follows respectively:89.2%/78.7% for 1 year,82.0%/74.7% for 3 years and 67.0%/58.4% for 5 years.Twelve cases have survived for more than 10 years.Experience in renal transplantation for 15 years reveals(1)Factors of raising graft survival rate are multiplicate.Among them high quality of procuration and transplantation of donor kidneys are most important;(2) In era of cyclosporine A,ABO matching and lymphocytes toxicity assay should be still persistent,(3)Infection is the main cause of failue in transplantation. Prevention of infection should be carried out in the whole course of pre-,post-operation and during operation;(4)Strengthening the work of postoperative follow-up and directing the patients'treatment during convalescent period must be emphasized.It is most significant for long term survival rate.
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