淋巴因子相应靶细胞的小剂量辐射效应  

EFFECT OF LOW DOSE RADIATION ON THE TARGET CELLS TO LYMPHOKINES RELATED

作　　者：刘伟宏[1] 李修义[1] 刘树铮[1] 

机构地区：[1]白求恩医科大学放射生物教研室

出　　处：《辐射研究与辐射工艺学报》1994年第2期75-78,108,共5页Journal of Radiation Research and Radiation Processing

基　　金：国家自然科学基金

摘　　要：观察了单次小剂量Ｘ射线全身照射后Ｃ５７ＢＬ／６小鼠胸腺细胞ＩＬ－１反应性和脾细胞ＩＬ－２反应性的变化。发现在１００ｍＧｙ以内的小剂量照射后，整个胸腺和脾脏的细胞数趋于增多，胸腺细胞对ＩＬ－１的反应性和牌细胞对ＩＬ－２的反应性趋于增强，体外照射ＩＬ－２依赖株ＣＴＬＬ－２细胞亦出现同样的反应趋势，但统计学处理与对照组比较均无明显差异。The changes of reactivities of thymocyte to IL-1 and splenocyte to IL-2 were studied in C 57 BL/6 mice after whole body X-irradiation with low doses. It was found that the number of thymocyte and splenocyte was increased,the reactivities of thymocyte to IL-1 and splenocyte to IL-2 also showed a tendency to increase after X-irradiation with low doses below 100 mGy, but the increase was statisticaly not significant. There was a same effect of low dese radiation on the CTLL-2, growing dependent on IL-2, irradiated in vitro.

关 键 词：小剂量辐照 生物效应 淋巴细胞 

分 类 号：Q691.5[生物学—生物物理学]