缩醛、缩酮在C＿pT＿iCl＿3／KI试剂体系中的脱保护作用  

CONVERSION OF ACETALS AND KETALSTO CARBONYL COMPOUNDS PROMOTED BY C_pTiCl_3-KI

作　　者：张玉兰[1] 许主国[1] 晁党校[1] 李平任[1] 吴绍祖[1] 

机构地区：[1]兰州大学化学系,兰州医学院

出　　处：《甘肃科学学报》1994年第2期62-66,共5页Journal of Gansu Sciences

摘　　要：缩醛、缩酮能在Ｃ＿ｐＴ＿ｉＣｌ＿３／ＫＩ作用下，在３０℃乙醚中转化为相应的羰基化合物。实验结果表明：非环状缩醛、缩酮比环状缩醛、缩酮易于脱保护；脂肪族缩醛、缩酮比芳香族缩醛、醛酮易于脱保护。实验结果同时表明，ＫＩ是缩醛、缩酮脱保护的有效的助催化剂，使用Ｃ＿ｐＴ＿ｉＣｌ＿３／ＫＩ比单独使用Ｃ＿ｐＴ＿ｉＣｌ＿３更有效。The reduction of acetals and ketals from aromatic or aliphatic aldehydes and ketons with C_p-TiCl_3-KI system in Et_2O at 30℃ affords the correspounding carboyl compounds.The results in-dicated:acyclic acetals and ketals can be more easily reduced than cyclic acetals and ketals,aro-matic acetals and ketals require a longer reaction time than aliphatic acetals and ketals,and it isclear known that KI is an effective cocatalyst,the mixture C_pTiCl_3-KI is more effective and mildfor the conversion of acetals and ketals to carbonyl compounds than C_PTiCl_3 alone.

关 键 词：三氯一茂钛 缩醛 缩酮 脱保护作用 

分 类 号：O632.3[理学—高分子化学]