雷公藤活性单体的筛选（一）  

Selection of active monomer of Tripterygium Wilfordii Hook

作　　者：夏金华[1] 吴厚生[1] 秦万章[1] 

机构地区：[1]上海医科大学免疫学教研室,上海医科大学附属中山医院皮肤科

出　　处：《赣南医学院学报》1994年第1期9-11,共3页JOURNAL OF GANNAN MEDICAL UNIVERSITY

摘　　要：通过雷公藤单体对淋巴细胞的增殖抑制及其毒性试验，从１５种单体中筛选出３种具有强免疫抑制效应但无毒副作用的活性单体Ｍ８，Ｍ１２和Ｍ１４，发现三种单体的抑制作用均大于甲基强的松龙。Three active monomers M8,M12and M14 that have strong immune-inhibition and no cyto to xicy effect have been selected from total fifteen monomers according to the inhibition effects of lymphocyte proliferation and its cytotoxity effects.Their inhibition effects have been found stronger than Methylprednisolone.

关 键 词：雷公藤 药理学 单体 筛选 

分 类 号：R282.710.5[医药卫生—中药学]