刺激家兔海马对扣带回前部痛单位电活动的作用  

EFFECT OF HIPPOCAMPAL STIMULATIONON ELECTKIC ACTIVITY OF THE PAIN UNITS OF THE ANTERIOR PART OF CINGULATE CORTEX IN RABBITS

作　　者：莫书荣 黄忠致 卢树斌 

出　　处：《广西医科大学学报》1994年第2期181-184,共4页Journal of Guangxi Medical University

摘　　要：用玻璃微电极记录方法在清醒麻痹的家兔上探讨海马对扣带回前部（ａＣＣ）痛单位的作用及其可能机制。结果发现，ａＣＣ的痛单位占引导神经无数的８．６％；３６．３％的痛单位对刺激海马起反应；脑室注射酚妥拉明或氟咙哇醉可阻断刺激海马对ａＣＣ痛单位的影响效应。提示：ａＣＣ参与痛信息的管理；海马可能调节ａＣＣ痛单位的活动；去甲肾上腺素、多巴胺及相应受体可能参与共调制。This study using the micro-electrod recording method investigated the effect ofhippocampal stimulation on the pain units ofthe anterior part ofcingulate cortex(aCC) in con- seious paralyticrabbits.The resuLts showed:the pain units of aCC amounted to 8.6% of theneurons recorded;36.3 % of these pain units responded tohippocampal stimulation;andintracerebroventricular injection of phentolamine(100μg in 30 μl) or haloperidol(100 μg in 30μl)could block the response of the pain units to hippocampal stimulation. These results suggestthat aCC participates in the management ofpain; the hippocampus may modulate the activity ofthe pain units of aCC;and norepinphrine,dopamine and their receptors possibly are involved insuch mechanism.

关 键 词：痛单位 海马 酚妥拉明 氟哌啶醇 

分 类 号：R338.26[医药卫生—人体生理学]