心肌梗塞患者自然杀伤细胞活性检测  

Reaction of natural killer cell activity to acute myocardial infarction

作　　者：李莉[1] 张永珍[1] 侯凤喜 杨俊敏[1] 

机构地区：[1]河南医科大学第一附属医院内科

出　　处：《河南医科大学学报》1994年第2期114-116,共3页Journal of Henan Medical University

摘　　要：用１２５ＩＵｄＲ释放法测定１７例急性心肌梗塞（ＡＭＩ）后一周内的外周血自然杀伤（ＮＫ）细胞活性，并与１３例陈旧性心肌梗塞（ＯＭＩ）及５８例正常人对照。结果表明：ＡＭＩ组ＮＫ细胞活性明显低于正常组及ＯＭＩ组（Ｐ＜０．０１）。ＡＭＩ组中，梗塞面积广泛者ＮＫ细胞活性明显低于梗塞面积局限者（Ｐ＜０．０１）。提示ＮＫ细胞活性可作为ＡＭＩ诊断和预后判断的一个辅助参考指标。Natural killer(NK) cell activity was measured in 17 patients in the first week of acute myocardial infarction (AMI) and 13 patients with old myocardial infarction(OMI).58 norma subjects were taken as control,The results showed that NK cell activity in the patients with AMI was depressed when compared with the controls and the patients with OMI (P<0.01).NK cell activity in the patients with extensive AMI was lower than that of the patients with local AMI(P<0.01).The mechanism of the depressed NK cell activity in AMI was discussed.It was suggested that the detection of peripheral blood NK cell activity may have practical significance for the diagnosis of AMI and it may be used as a reference index for the prognosis of AMI.

关 键 词：杀伤细胞 活性 心肌梗塞 

分 类 号：R542.22[医药卫生—心血管疾病]