广枣－钾停搏液对心肌保护作用的研究  

MYOCARDIAL PROTECTIVE EFFECT OF GUANGZAO-POTASSIUM CARDIAC ARREST SOLUTION IN DOGS

作　　者：周新民[1] 詹樾[1] 江亚平[1] 湖建国 

机构地区：[1]湖南医科大学第二附属医院心外科,湖南省心血管疾病研究所

出　　处：《湖南医科大学学报》1994年第5期398-400,共3页Bulletin of Hunan Medical University

摘　　要：采用犬体外循环模型，观察广枣－钾停搏液在低温下对心脏缺血９０ｍｉｎ，再灌注４５ｍｉｎ的保护作用。实验结果显示：广枣－钾停搏液组心功能恢复率较单纯托马氏停搏液组为高；心肌水、钙含王及氧自由基含量明显降低。电镜观察心肌超微结构亦显示前者的保护作用明显优于后者。广枣与托马氏液合用，能加强对心脏的保护作用。本文对广枣护心的作用机制作了讨论。Fructus choerospondiatis)is a kind of Mongolian traditional medicinalherbs. Myocardial protective effect of guangzao-potassium cardiac arrest solution(GPS)wereevaluated in dog extracorporal circulation model after 90 min ischemia and after 45 min reper-fusion under hypothermic condition。The results showed that the heart function recovery ratewas higher in GPS group than that of the simple St Thomas'hospital solution(STS)group.Myocardial water content,calcium ion and oxygen free radical levels of GPS groupwere significantly lower than that of STS group,The ultrastructural study confirmed its bet-ter myocardial protection. Pharmacological mechanism of Guangzao-potassium solution wasdiscussed.

关 键 词：心内直视手术 广枣 体外循环 心肌保护 氧 蒙药 

分 类 号：R654.1[医药卫生—外科学] R291.2[医药卫生—临床医学]