细胞色素P—450模拟体系的活性中间体-氧配位铬(V)四苯基卟啉配合物的分离、表征和氧化反应  

Isolation, Characterization and Oxidation Reaction of Active Intermediates of Cytochrome P-450 Model System Oxochromium (Ⅴ) Tetraphenylporphyrin Complexes

作　　者：舒火明[1] 谷淑珍[1] 金日镇[1] 刘永盛[1] 金钟声[1] 

机构地区：[1]中国科学院长春应用化学研究所,长春130022

出　　处：《化学学报》1994年第5期468-473,共6页Acta Chimica Sinica

基　　金：国家自然科学基金资助的课题

摘　　要：氮气保护下二氯甲烷中铬(Ⅲ)四苯基卟琳衍生物在-40℃与亚碘酰苯反应,分离得氧配位铬(V)四苯基叶啉配合物:O=Cr(V)TPP(CI)PhI,O—Cr(V)TPP(N_3)PhI,O—Cr(V)TPP(p-CH_3O-C_6H_4O)1/2PhI.已经元素分析、可见、红外、顺磁、核磁和质谱法结构表征.这些配合物能氧化苯乙烯,环己醇,环己烯和环己烷,可作为细胞色素P—450模拟体系的活性中间体.Oxochromium (V ) tetraphenylporphyrin complexes. O =Cr (V ) TPP (Cl) Phl. O =Cr-(V) TPP (N3) PhI and O =Cr (V )TPP (p-CH3OC6H4O)1/2PhI were isolated from the reaction of Cr (333333333) TPP (Cl). Cr (33333333 ) TPP (N3) Py or Cr (333333333) TPP (p-CH3OC6H4O) THF with iodosylbenzene in dichloromethane at -40ccccccccccc under nitrogen. They were characterized by elemental analyses, visible, infrared. ESR. NMR and mass spectra. They can oxidize styrene. cyclohexanol. cyclohexene and cyclohexane. They are the active intermediates of cytochrome P-450 model systems.

关 键 词：氧配位 铬卟啉 络合物 细胞色素 

分 类 号：O614.611[理学—无机化学]