二氯苯醚菊酯浸泡蚊帐防制大劣按蚊及疟疾的现场研究  

A FIELD TRIAL OF BEDNETS IMPREGNATED WITH PERMETHRIN FOR THE CONTROL OF ANOPHELES DIRUS TRANSMITTED MALARIA IN HAINAN ISLAND,CHINA

作　　者：李祖资[1] 李明馨 潘波[1] 罗均明 黄祺林[1] 

机构地区：[1]广东省寄生虫病防治研究所,海南省热带病防治研究所

出　　处：《寄生虫与医学昆虫学报》1994年第4期32-39,共8页Acta Parasitologica et Medica Entomologica Sinica

基　　金：联合国开发计划署/世界银行/世界卫生组织热带病研究培训特别规划处的部分经费资助

摘　　要：１９８９年４月～１９９２年３月在海南万宁县北大乡进行了二氯苯醚菊酯浸泡蚊帐防疟试验。在现场选择１０个自然村６１２６人为实验区。浸帐前一年进行了流行病学基本数据调查，１９９０年４～５月和１９９１年４月分别用二氯苯醚菊酯５００ｍｇａｉ／ｍ２剂量浸泡蚊帐，浸帐率９８．２％，两次药帐人口覆盖率分别为７３．６％和７３．５％。实验区浸帐前（１９８９年６～１２月）平均月发病率９．９６‰，浸帐后分别降为３．４５‰（１９９０）和２．０７‰（１９９１），比浸帐前同期分别下降６５．４％和７９．２％。其中恶性疟下降尤其迅速而明显。三年试验结果表明，二氯苯醚菊酯浸泡蚊帐对大劣按蚊自然种群密度及疟疾传播均有明显的防制效果。A field trial of permethrin-impregnated bednets for the control of malaria transmitted by An.dirus was carried out in Beida district, Hainan Island. From April 1989 to March 1990, the pretrial baseline data on malaria epidemiology were obtained in both study and control areas. There is a population of 6248, 75.4% of them with nets and 98.2% of which were impregnated once a year at the dosage of 500mg ai/m2 in April of 1990 and 1991 in the study area. The anopheline density measured by human baits during the peak season(May to Sept.) was 3.1 before treatment and dropped to 1.2 and 0.5 after treatment in 1990 and 1991, being of 82.7% and 84.6% decline respectively. In the control area the corresponding densities were 2.2,4.9 and 2.3 respectively. The mean monthly malaria incidence from June to December was 9.96‰ in the study area before treatment and dropped to 3.45‰ and 2.07‰. during the same periods in 1990 and 1991 after treatment, meanwhile the incidence of malignant malaria reduced by 93% and 87%, respectivcly.

关 键 词：二氯苯醚菊酯 蚊帐 大劣按蚊 疟疾 发病率 

分 类 号：R978.61[医药卫生—药品] R531.301[医药卫生—药学]