氟、锂、铝离子对孕酮去极化作用的影响  

The effect of Fluorine ion,Lithiumion ion and Aluminum ion on depolarization of pregnendione

作　　者：杨殿生[1] 王凯[1] 王羽峰[1] 张桂芳 赵晓秀 

机构地区：[1]佳木斯医学院生理教研室 [2]黑化幼儿园保健室

出　　处：《佳木斯医学院学报》1994年第3期12-13,共2页

摘　　要：为探讨孕酮致膜电位降低的机理,我们选择性应用 GS（兴奋性 G 蛋白）激动剂 F^-,钙调蛋白抑制剂 AL²⁺和干扰磷酯酰肌醇代谢,减少胞内 Ca^2÷释放的 Li⁺处理卵母细胞,并观察孕酮作用。In order to investigate the mechanism for which pregnendioe decreases membrane potential,we applied GS,active agent—Fluorineion,calmodulin depressing agent-Aluminum ion and Lithiumion ion which can interfere phosphatidyl inositol metabolism and decrease Calcium ion release in the cell to treat ooeyte to observe the function of pregnendione.The results showed that both Fluorine ion and Lithiumion ion caused ultrodepolarization of membrane potential and Aluminum ion had no significant effect on membrane potential,but sharply reduced pregnendione,s depolarization once used with pregnendione.

关 键 词：氟 锂 铝 孕酮 膜电位 

分 类 号：R714.12[医药卫生—妇产科学]