人参多糖、刺五加提高冷适应能力的研究  

STUDY ON ENHANCING COLD ADAPTIVE CAPACITY BY POLYSACCHARIDE FROM RADIX GINSENG AND CIWUJIA

作　　者：杨成君[1] 杨义军[1] 郭凤鸣[1] 吴建良[1] 宋思聪[1] 

机构地区：[1]沈阳军区后勤部军事医学研究所,81156部队医院

出　　处：《解放军预防医学杂志》1994年第6期436-439,共4页Journal of Preventive Medicine of Chinese People's Liberation Army

摘　　要：本文选择入伍二年北方籍战士６０人，分成１Ⅰ、Ⅱ、Ⅲ组，分别服用人参多糖、刺五加和安慰剂口服液。观察服用上述药物是否有提高和加速冷适应能力的作用。其结果（１）Ⅰ、Ⅱ组尿ＶＭＡ排出量第１０、２０ｋ与实验前比有明显增加（Ｐ＜０．０５和Ｐ＜０．０１），Ⅲ组尿ｖＭＡ排出量低于Ⅰ、Ⅱ组（Ｐ＜０．０５）。（２）血液流变学指标（全血粘度，总周阻力，微循环半更新时间，心肌氧耗指数）Ⅰ、Ⅱ组比实验前有明显差异（Ｐ＜０．０５）。（３）手指在０℃冰水中，实验前三组均有疼痛感，服药期间第５、１０天，Ⅰ、Ⅱ组与实验前比较，疼痛者明显减少（ｐ＜０．０５和ｐ＜０．０１），第２０天Ⅰ、Ⅱ组已无疼痛者，而Ⅲ组仍有２０％人有疼痛。通过本次实验观察说明，此二药可能有提高或促进冷习服作用。n this study 60 soldiers,who have enlisted for military service overtwo years,were choosed and divided into three groups Ⅰ Ⅱ and Ⅲ receivingthe polysaccharide from Radix Ginseng,the Ciwujia(Radix Acantho para-cis senticosi)and the placebo,respectively,in order to observe the effects in enhancing cold abaptive capacity with these drugs.The results were that(1)the urinary output of VMA(the products of catecholaminemetabolism)in group Ⅰ and Ⅱ were increased significantly on the 10thand 20th days as compared with that before experiment,and in group III,it was significant lower than in group1,II at the same time;(2)the he-morrheological norms(including lvhole blood viscosity,resistance of tolalperipheral blood,semiturnover time of microcirculation and mvocardialoxygen-consumptive index)in group I,II were signifcant different as com一pared with that before experimeiit (P<0.05),(3)the pain sensation of fin-gers immersed in ice water(0 ℃)occured in all three groups before experi-ment,while on the 5th and l0th days the number of pain persons decreasedsignificantly(P<0.50 and<0.01);and furthermore on the 20th day nobodyfelt pain in grup I and II,but the number of pain persons accounted for20%of total persons in group III.This experimental observation showedthat the two drugs may enhance or promote the adaptation to cold。

关 键 词：人参多糖 刺五加 冷适应 人参 

分 类 号：R285.6[医药卫生—中药学]