大鼠异体神经移植后再生神经的荧光逆行标记  

FLUORESCENCE LABELLING NERVE REGENERATION THROUGH NERVE HOMOGRAFT

作　　者：曾志诚[1] 帅建中[2] 邓展生[3] 任力锋[4] 谢嘉平[4] 刘喜林[4] 

机构地区：[1]湖南医科大学人体解剖学教研室,长沙410078 [2]湖南医科大学神经生物学研究室 [3]湘雅医院骨科 [4]湖南医科大学医学工程研究室

出　　处：《解剖学杂志》1994年第6期547-550,共4页Chinese Journal of Anatomy

摘　　要：用Wistar大鼠作为实验模型,切除1cm坐骨神经,再用同系Wistar大鼠坐骨神经行异体桥接,修复坐骨神经的缺损.用Fluoro-Gold或Fast Blue两种荧光标记物,进行示踪检验,证实Wistar鼠异体神经桥接能修复周围神经的缺损.In the experiment, 1 cm of sciatic nerve of wistar rats was cut off and then the gap was bridged with nerve homograft of Wistar rats. Two kinds of fluorochromes fluor -gold(FG) and Fast blue (FB) were used in tracing the continuity of the cut sciatic nerve. The results demonstrated that the retrograde fluorescent tracing with FG and FB was a good labelling method used to detect the regeneration of peripheral nerve fibres and that the nerve bridge with homograft of Wistar rats were suitable bridging method for peripheral nerve reconstruction.

关 键 词：神经再生 坐骨神经 神经移植 荧光逆行标记 

分 类 号：R622.3[医药卫生—整形外科] R322.85[医药卫生—外科学]