国产β－胡萝卜素治疗红细胞生成性原卟啉病  

β-carotene therapy for erythropoietic protoporphyria

作　　者：阎春林[1] 廖康煌[1] 

机构地区：[1]上海医科大学皮肤病学研究所

出　　处：《临床皮肤科杂志》1994年第5期258-259,共2页Journal of Clinical Dermatology

摘　　要：采用临床对照试验观察口服β－胡萝卜素治疗红细胞生成性原卟啉病的光敏反应，治疗组３３例，显效率为６０％，总有效率１００％。除皮肤黄染外未观察到其它不良反应。掌心皮肤黄染常出现在治疗后２～６周，随后病人可在指导下逐渐增加日晒时间。皮肤黄染可作为调整用药剂量和指导病人适当增加日晒时间的指标。In a controlled clinical study, oral β-carotene was used to reduce the severity of photosensitivity reactions in patients with erythropoietic protoporphyria.Out of 33 cases treated with β-carotene, 60% showed significant response,and total response rate was 100%.Except the skin yellowness,no other adverse reaction was observed. Yellowness of palms usually occurs within two to six weeks of therapy,then the patients may be instructed to increase the gradually exposure to sunlight.

关 键 词：红细胞生成性 原卟啉病 胡萝卜素 

分 类 号：R758.405[医药卫生—皮肤病学与性病学]