原发性高血压病人红细胞^（86）Rb主动摄取率测定  

Study on active^(86)Rb uptake rates of the erythrocytes in different age groups with essential hypertension

作　　者：张世联[1] 符云峰[1] 刘建功[1] 

机构地区：[1]河北省医学科学院生化室

出　　处：《临床心血管病杂志》1994年第4期198-200,共3页Journal of Clinical Cardiology

摘　　要：本实验采用同位素８６Ｒｂ代替Ｋ＋，测定３７例原发性高血压（ＥＨ）病人红细胞的８６Ｒｂ主动摄取率。发现青年ＥＨ组病人８６Ｒｂ摄取率（７．３３ｎｍｏｌ／ｍｌ细胞·分－１）较对照组（４．２８ｎｍｏｌＲｂ／ｍｌ细胞·分－１）增高（Ｐ＜０．０５），而高年龄ＥＨ组病人（４．１６ｎｍｏｌＲｂ／ｍｌ细胞·分－１）较对照组（５．９０ｎｍｏｌＲｂ／ｍｌ细胞·分－１）降低（Ｐ＜０．０５）；另将病人平均动脉压与摄取率进行相关统计分析，结果呈负相关，（ｒ＝－０．３６，Ｐ＜０．０５）。表明不同年龄、不同血压的ＥＨ患者，对红细胞８６Ｒｂ主动摄取率是不一致的。Abstract The active 86Rb uptake rates of erythrocytes from essential hypertension patients (EHP)have been studied in this article. 37 EHP were divided into 3 groups,according to ages,21-40, 41-60 and≥61. The results showed that active 86Rb uptake in the young group of EHP was higher significantly than control group, they were7.33±3.72 and 4. 28± 1. 03(nmol/L cell/min)respectively (P<0.05). The activity in middle age group decreased from 5. 90±2. 28 in control group to 4. 16±2.45(P<0.05). The≥61-group also decreased from 6. 30±2. 16 to 4. 85±2. 91,but it had not statistical significance. In addition, we further demonstrated that the mean artery pressure was negatively related with the activity of active 86Rb uptake.(r=-0. 36,P<0.05). The results indicate that the changes of active 86Rb uptake in EHP reveale an age difference.

关 键 词：高血压 原发性 红细胞 铷86 摄取率 

分 类 号：R544.102[医药卫生—心血管疾病]