内蒙古苦豆子Sophoraalopecuroides生物碱成分及分离研究  

Study on the Constituents and Separation of Alkaloids from Nei Menggu Sophora alopecuroides

作　　者：张文[1] 莫日根[1] 许慧珍 乌乐[1] 

机构地区：[1]内蒙古大学化学系

出　　处：《内蒙古大学学报（自然科学版）》1994年第6期661-664,共4页Journal of Inner Mongolia University：Natural Science Edition

基　　金：国家自然科学基金

摘　　要：用薄层扫描法测定了内蒙古苦豆子中主要生物碱的含量，真空液相层析法分离总碱得八种结晶。其中七种已知生物碱。通过熔点、薄层定性、红外、核磁等理化分析比较确认为槐果碱、苦参碱、槐定碱、槐胺碱、氧化苦参碱、金雀花碱和Ｎ－甲基金雀花碱。晶（１）经ＩＲ，￣１ＨＮＭＲ及ＭＳ谱表征，初步认为是槐定碱的Ｎ－氧化物，是首次从国产苦豆子植物分离得到．he contents of the main alkaloids in the seed of Nei Menggu Sophora alopecuroides were de-termined by the thin layer scanning method.The total alkaloids were separated by the VacuumLiquid Chromatography.Eight alkaloids were isolated.On the basis of M.P.,IR,￣1H-NMR andMS spectra these alkaloids were identified as sophocarpine,matrine,sophoridine, sophoramine,oxymatrine,cytisine,N-methylcytisine and sophoridine N-oxide.Among them sophoridine N-ox-ide was isolated from Chinese Sophora alopecuroides for the first time,and its structure was pre-liminary identified.

关 键 词：真空液柏层析 苦豆子 生物碱 槐树属 

分 类 号：Q949.751.9[生物学—植物学]