乙型肝炎患者血清抗—HCV临床意义探讨  

Consideration on Clinical Significance of Anti- HCV in HBV Patients'Sera

作　　者：杨晶[1] 陈青锋[1] 王华信[1] 杨彦麟[1] 肖萍[1] 郭振华[1] 安平[1] 谢晨[1] 

机构地区：[1]兰州医学院传染病研究室

出　　处：《宁夏医学杂志》1994年第3期148-150,共3页Ningxia Medical Journal

摘　　要：应用第二代抗─ＨＣＶ酶免疫试验检测了１９４例各型乙型肝炎患者血清丙型肝炎病毒抗体（抗─ＨＣＶ），结果抗─ＨＣＶ阳性率为２３．２％，其中，重型肝炎（ＳＨ）者为４４．４％、原发性肝癌（ＰＨＣ）者为３７．５％、肝硬化（ＣＩＲ）者为３６．６％、慢活肝（ＣＡＨ）者为２６．１％、慢迁肝（ＣＰＨ）者为１６．７％、急性肝炎（ＡＨ）者为７．１％、无症状ＨＢｓＡｇ携带者（ＡＳＣ）的为６．７％，提示肝病越严重，其抗─ＨＣＶ的阳性率就越高。还发现重叠感染ＨＣＶ的乙型肝炎患者之ＨＢＶ复制率较低。Using second-pgeneration enzyme-linked immunoassay,anti-HCV was determined In 194 patients with various types of viral hepatitis B(HB).The total positive rate of ati-HCV in these patients was 23.2%;of which,severe hepatitis(SH)'s being 44.4%, Primary hepatocellular carcima(PHC)'s being 37.5%, hepatic cirrhosis(CIR)'s being 36.6% chronic active hepatitisCAH)'s, being 26.1%,chronic persistent hepa-titis(CPH)'s being 16.7%, acutehepatitis(AH)'s being 7.1%and, asymptomatic HBsAg carriers(ASC)'s being.7%. It was indicated that,the severe the particular type of HB,the greater the anti-HCV positive rate.would be and,the replication rate of HBV marker was fower in HB patients with superinfection of HCV than that in HB alone.

关 键 词：乙型肝炎 丙型肝炎病毒 抗体 血清 

分 类 号：R512.620.3[医药卫生—内科学]